Effects of Renal Sympathetic Denervation in Diastolic Heart Function in CKD Refractory Hypertensive Patients

Márcio Galindo Kiuchi, Miguel Luis Graciano, Maria Angela Magalhães de Queiroz Carrei, Tetsuaki Kiuchi, Jocemir Ronaldo Lugon

Abstract


Diastolic heart failure (HF) is an important factor that increases mortality related to the cardiovascular system in patients with chronic kidney disease (CKD) whose extent of kidney function deterioration differs. As a non-invasive method to allow early assessment, the E/e’ ratio estimated by tissue Doppler imaging can predict mortality and cardiovascular events in CKD patients with diastolic dysfunction. The current study evaluated 15 patients with CKD and left ventricular hypertrophy (LVH), who were selected according to a previously published protocol. In the present study, we reported for the first time the improvement in diastolic parameters measured by echocardiography in CKD patients with resistant hypertension and left ventricular hypertrophy 6 months after renal sympathetic denervation (RSD). Our results suggest that RSD in this kind of patients seems to avoid the progression to diastolic HF.


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DOI: https://doi.org/10.17987/jatamis.v1i0.203

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Copyright (c) 2016 Márcio Galindo Kiuchi, Miguel Luis Graciano, Maria Angela Magalhães de Queiroz Carrei, Tetsuaki Kiuchi, Jocemir Ronaldo Lugon

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ISSN: 2518-6140 (on-line version)